abstract：BACKGROUND:There is a paucity of data concerning the risks associated with warfarin in hemodialysis (HD) patients. We compared major bleeding episodes in this group with HD patients not receiving warfarin and with a cohort of non-HD patients receiving warfarin. METHODS:A retrospective review of 141 HD patients on warf...

journal_title：Clinical nephrology

authors： Phelan PJ,O'Kelly P,Holian J,Walshe JJ,Delany C,Slaby J,Winders S,O'Toole D,Magee C,Conlon PJ

更新日期：2011-03-01 00:00:00

abstract：:Acute promyelocytic leukemia (APL) with transcripting three isoforms of mRNA from PML-RAR alpha fusion genes following renal transplantation has never been reported in the literature. A 39-year-old man received a cadaveric renal allograft for IgA chronic kidney disease in 2006 and was consecutively immunosuppressed by...

journal_title：Clinical nephrology

authors： Lai CP,Chang CC,Chung CY,Chen ML

更新日期：2011-02-01 00:00:00

abstract：AIMS:This study evaluated whether arteriovenous access (AVA) creation before hemodialysis might affect the rate of decline of renal function. METHODS:This was a retrospective, case-control study comparing two groups of 80 patients each. The AVA group underwent AVA creation more than 2 months before initiation of chron...

journal_title：Clinical nephrology

authors： Jeong JU,Kim HK,Cho YP,Kwon TW,Kim SB

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Insulin resistance is an independent predictor of cardiovascular mortality in hemodialysis (HD) patients. Inflammation plays an important role in insulin resistance, and adipocytokines, including tumor necrosis factor-alpha and leptin, can induce insulin resistance. However, data on insulin resistance and er...

journal_title：Clinical nephrology

authors： Abe M,Okada K,Soma M,Matsumoto K

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Hemodialysis patients often present with increased concentrations of tryptophan catabolites perhaps related to an enhanced activity of tryptophan-degrading enzyme indoleamine 2,3-dioxygenase (IDO) that is inducible by pro-inflammatory stimuli. The often chronic inflammation and immune activation status in di...

journal_title：Clinical nephrology

authors： Koenig P,Nagl C,Neurauter G,Schennach H,Brandacher G,Fuchs D

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND AIMS:this study evaluated the factors associated with bone mineral density (BMD) in chronic peritoneal dialysis (CPD) patients. METHODS:in this cross-sectional study in 91 stable CPD patients, BMD was measured using dual-energy X-ray absorptiometry. Markers of bone turnover (iPTH, osteocalcin, bone alka...

journal_title：Clinical nephrology

authors： Jeong JU,Lee HK,Kim YJ,Kim JS,Kang SS,Kim SB

更新日期：2010-11-01 00:00:00

abstract：:Fibromuscular dysplasia (FMD) is a non-atheromatous, non-inflammatory, multifocal segmental angiopathy. FMD is the most common cause of pediatric renovascular hypertension. Aneurysmal formation of the main renal artery and distal branches is a rare complication of FMD in infancy. We report an 8-month-old boy with FMD ...

journal_title：Clinical nephrology

authors： Takano K,Kawasaki Y,Imaizumi T,Ohara S,Takeyama A,Suyama K,Hashimoto K,Hosoya M

更新日期：2010-11-01 00:00:00

abstract：:Indigenous people in Australia and New Zealand experience rates of ESKD several times higher than non-indigenous people. This relative rate is highest among people aged 45 - 54 for Aboriginal Australians, and 65 - 74 years for Maori. The majority of this is driven by diabetic nephropathy. Both groups have lesser utili...

journal_title：Clinical nephrology

authors： McDonald S

更新日期：2010-11-01 00:00:00

abstract：:Chronic kidney disease (CKD) is a common and costly health problem in the Middle East. The incidence of CKD is still unknown, and the incidence of end-stage renal disease (ESRD) is estimated at 100 - 140 incident cases per million population in the Middle East countries. Most of the available statistics about prevalen...

journal_title：Clinical nephrology

authors： Shaheen FA,Souqiyyeh MZ

更新日期：2010-11-01 00:00:00

abstract：:Most dialysis patients are on 5 - 10 medications. The costs of these medications vary widely, ranging from pennies per day for water soluble multivitamins, to several thousand dollars per year for erythropoietin-stimulating agents. In Canada, public funding for drug therapies is undertaken by each province, with wide ...

journal_title：Clinical nephrology

authors： Mendelssohn DC

更新日期：2010-11-01 00:00:00

abstract：AIM:The aim of this study was to investigate the effects of ezetimibe on high-density lipoprotein (HDL) subspecies and serum amyloid A (SAA), an apolipoprotein mainly bound and transported by HDL particles, in patients with end-stage renal disease (ERSD), a condition typically characterized by high SAA- and low HDL-cho...

journal_title：Clinical nephrology

authors： Hirano T,Nohtomi K,Nakanishi N,Watanabe T,Hyodo T,Taira T

更新日期：2010-10-01 00:00:00

abstract：:Anemia secondary to end-stage renal disease (ESRD) is an important but complex syndrome which directly contributes to significant morbidity and mortality in this patient population. The interactions between uremia, bone marrow biology and erythropoietin (EPO) responsiveness are of significant interest to improve our b...

journal_title：Clinical nephrology

authors： Rioux JP,Chan CT

更新日期：2010-09-01 00:00:00

abstract：:Vascular lesions are encountered frequently in renal biopsy specimens of patients with systemic lupus erythematosus (SLE) and can present in a variety of morphologic forms. True renal lupus vasculitis (TRLV) is one of the rare vascular lesions associated with lupus nephritis that has been infrequently reported in the ...

journal_title：Clinical nephrology

authors： Abdellatif AA,Waris S,Lakhani A,Kadikoy H,Haque W,Truong LD

更新日期：2010-08-01 00:00:00

abstract：AIM:Limitations of conventional phosphate binders have led to the development of novel non-calcium, non-aluminium agents for use in patients with chronic kidney disease (CKD). The iron-based agent PA21 (stabilized polynuclear iron(III)-oxyhydroxide) has high phosphate binding capacity in vitro. This study was undertake...

journal_title：Clinical nephrology

authors： Geisser P,Philipp E

更新日期：2010-07-01 00:00:00

abstract：:A 62-year-old man was admitted to the ophthalmologic department for operation of retinal detachment. Mannitol and acetazolamide were prescribed to reduce intraocular pressure. Seven days after operation, gradual onset of drowsy consciousness occurred. The laboratory findings of hypertonic hyponatremia (109 mEq/l), hyp...

journal_title：Clinical nephrology

authors： Tsai SF,Shu KH

更新日期：2010-07-01 00:00:00

abstract：:Orally-administered steroids often induce osteonecrosis of the femoral head. In cases of Perthes disease, osteonecrosis of the femoral head occurs in children due to an unknown cause. Our subject was a 4-year-old boy who had to be given large amounts of steroids because of frequently relapsing nephrotic syndrome (FRNS...

journal_title：Clinical nephrology

authors： Mori K

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:IgG4-related tubulointerstitial nephritis (TIN) shows characteristic serum IgG4 elevation and increased IgG4-positive plasma cells in the renal interstitium, and inclusion of TIN as an IgG4-related systemic disease has been suggested. IgG4 is the rarest IgG subclass and is a Th2-dependent isotype with low af...

journal_title：Clinical nephrology

authors： Nakashima H,Miyake K,Moriyama M,Tanaka A,Watanabe M,Abe Y,Sato H,Nakamura S,Saito T

更新日期：2010-05-01 00:00:00

abstract：:Obstruction of the ureter as a cause of acute or chronic kidney injury in the transplanted kidney is unusual beyond the perioperative period. We present a case of ureteric obstruction, infection and septicemia caused by a large uterine leiomyoma in a patient 8 years post transplantation. Initial treatment comprised of...

journal_title：Clinical nephrology

authors： Abate M,Wadhwa NK,Nord EP

更新日期：2010-04-01 00:00:00

abstract：UNLABELLED:Recombinant human erythropoetin beta; (rHuEPO) has not only an erythropoietic effect but also appears to affect production of cytokines and may improve nutritional status of dialysis patients. Darbepoetin alpha; is a new erythropoiesis-stimulating protein with a threefold longer serum half-life when compared...

journal_title：Clinical nephrology

authors： Malgorzewicz S,Lichodziejewska-Niemierko M,Lizakowski S,Liberek T,Lysiak-Szydlowska W,Rutkowski B

更新日期：2010-03-01 00:00:00

abstract：UNLABELLED:Human serum paraoxonase (PON1) activity is reduced in standard hemodialysis (SHD) (4 hours, 3 days/week) patients. Home nocturnal hemodialysis (HNHD) (8 hours, 6 days/week), provides a greater dialysis dose resulting in a greater clearance of metabolites. Whether improvements in the metabolic milieu of HNHD ...

journal_title：Clinical nephrology

authors： Kannampuzha J,Darling PB,Maguire GF,Donnelly S,McFarlane P,Chan CT,Connelly PW

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Mental disorders are frequent in hemodialysis (HD) patients. Depression and anxiety along with physical co-morbidity affect quality of life (QOL). Uremia is associated with inflammation and release of cytokines by lymphomonocytes. Inflammatory cytokines are relevant in depression. The aim of this study was t...

journal_title：Clinical nephrology

authors： Montinaro V,Iaffaldano GP,Granata S,Porcelli P,Todarello O,Schena FP,Pertosa G

更新日期：2010-01-01 00:00:00

abstract：:Patients undergoing dialysis treatment have a high incidence of dyslipidemia. Rosuvastatin is a potent statin drug that improves overall lipid profiles in dyslipidemic patients. However, the pharmacokinetics of rosuvastatin has not been studied in patients with end-stage kidney disease undergoing chronic peritoneal di...

journal_title：Clinical nephrology

authors： Bologa R,Levine D,Parker T,Gordon B,Lanto A,Cheigh J,Stenzel K,Rubin A

更新日期：2009-12-01 00:00:00

abstract：AIM:To compare the difference of clinical curative effects of continuous ambulant peritoneal dialysis (CAPD) patients in China by using a two-cuff Swan neck catheter and a Tenckhoff catheter. METHODS:110 patients with end-stage renal disease (ESRD) were enrolled. They were divided into Group A (Swan neck catheter grou...

journal_title：Clinical nephrology

authors： Xie JY,Chen N,Ren H,Huang XM,Zhu P

更新日期：2009-11-01 00:00:00

abstract：AIMS:The aim of this crossover study was to compare the reduction of serum phosphorus (SP) with fixed doses of the non-calcium-containing phosphate binders lanthanum carbonate (LC) and sevelamer hydrochloride (SH) in hemodialysis patients. METHODS:Following washout (2 - 3 weeks), 182 patients with SP >or= 6.0 mg/dl an...

journal_title：Clinical nephrology

authors： Sprague SM,Ross EA,Nath SD,Zhang P,Pratt RD,Krause R

更新日期：2009-10-01 00:00:00

abstract：:Foreign body aspiration can be a life-threatening emergency requiring immediate intervention. However, unlike in children, clinical presentation of foreign bodies in adults often varies with regard to symptoms and signs and occurs without asphyxia. We here describe the case of a 65-year-old man on maintenance hemodial...

journal_title：Clinical nephrology

authors： David S,Merscher S,Schmidt-Guertler H,Kielstein JT,Kirchhoff T,Meier M

更新日期：2009-10-01 00:00:00

abstract：UNLABELLED:Interferon-gamma (IFN-gamma) is required for the acquired immune response involving maturation and activation of antigen-presenting cells (APC); both IFN-gamma production and activation of APC are impaired in ESRD patients on low-flux hemodialysis (HD). High levels of uremic toxins including beta2-microglobu...

journal_title：Clinical nephrology

authors： Lonnemann G,Bahlmann FH,Freise J,Hertel B,Dinarello CA

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Renal amyloidosis has emerged as an important differential diagnosis when heroin addicts are admitted to renal clinics with proteinuria and nephrotic syndrome. MATERIAL:We present nine heroin addicts with renal AA amyloidosis, a condition previously not encountered in Norway, who were admitted to our renal ...

journal_title：Clinical nephrology

authors： Manner I,Sagedal S,Røger M,Os I

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Septic shock is associated with vasopressin deficiency and hypersensitivity to its exogenous administration. The aim of this study is to review the 28-day survival rate, hemodynamic and renal effects of vasopressin therapy in refractory septic shock Japanese patients. METHODS:55 Japanese patients experienci...

journal_title：Clinical nephrology

authors： Sawa N,Ubara Y,Katori H,Hoshino J,Suwabe T,Takemoto F,Uchida N,Masuoka K,Wake A,Taniguchi S,Takaichi K

更新日期：2009-08-01 00:00:00

abstract：:Minimal change nephrotic syndrome (MCNS) usually is considered to have a good renal prognosis, but the frequency of relapses is a therapeutic challenge to physicians. The treatment of patients with multiple relapses remains a matter of controversy, because few controlled studies are available. We report the case of a ...

journal_title：Clinical nephrology

authors： Sawara Y,Itabashi M,Kojima C,Tabata H,Kamei D,Kawanishi K,Moriyama T,Sugiura H,Tsukada M,Takei T,Ogawa T,Yoshida T,Arai J,Uchida K,Tsuchiya K,Nitta K

更新日期：2009-07-01 00:00:00

abstract：AIMS:IgA nephropathy is one of the most common glomerular diseases in children. The aim of this study was to investigate the clinical and pathologic efficacy of methylprednisolone and cyclophosphamide in the treatment of primary pediatric IgA nephropathy. METHODS:11 patients with renal-biopsy-diagnosed Grade IV IgA ne...

journal_title：Clinical nephrology

authors： Jiang XY,Mo Y,Sun LZ,Yue ZH,Chen SM,Wu W

更新日期：2009-06-01 00:00:00

abstract：:We herein report the case of a 12-year-old boy with dense deposit disease (DDD) evoked by streptococcal infection. He had been diagnosed to have asymptomatic hematuria syndrome at the age of 6 during school screening. At 12 years of age, he was found to have macrohematuria and overt proteinuria with hypocomplementemia...

journal_title：Clinical nephrology

authors： Sawanobori E,Umino A,Kanai H,Matsushita K,Iwasa S,Kitamura H,Oda T,Yoshizawa N,Sugita K,Higashida K

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus (DM) and deficiency in n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFAs) are known to increase the incidence of cardiovascular disease (CVD). However, it has not yet been reported whether n-3 LCPUFAs are related to arteriosclerosis in patients under long-term hemodialysis (HD). METH...

journal_title：Clinical nephrology

authors： Hamazaki K,Terashima Y,Itomura M,Sawazaki S,Inagaki H,Kuroda M,Tomita S,Hirata H,Hamazaki T

更新日期：2009-05-01 00:00:00

abstract：:Fungi poisoning is quite frequent: in particular, Amanita phalloides has life-threatening toxicity. It is responsible for fulminant hepatitis, and also has renal toxicity. Herein, we report on a patient who developed acute renal failure after ingesting A. phalloides, which required definitive renal replacement therapy...

journal_title：Clinical nephrology

authors： Garrouste C,Hémery M,Boudat AM,Kamar N

更新日期：2009-05-01 00:00:00

abstract：AIM:Patients with end-stage renal disease (ESRD) have an increased mortality from cardiovascular disease (CVD). N-terminal pro-brain natriuretic peptide (NT-pro-BNP) is an independent predictor of mortality in patients with ischemic heart disease and congestive heart failure. Previous data have shown markedly elevated ...

journal_title：Clinical nephrology

authors： Svensson M,Gorst-Rasmussen A,Schmidt EB,Jorgensen KA,Christensen JH

更新日期：2009-04-01 00:00:00

abstract：:Persistent left superior vena cava (PLSVC) is the most common thoracic venous circulation anomaly and discovered incidentally during hemodialysis catheter insertion. PLSVC may have some clinical implications for nephrologists. PLSVC can create difficulties during catheter insertion and cause serious complications; it ...

journal_title：Clinical nephrology

authors： Jang YS,Kim SH,Lee DH,Kim DH,Seo AY

更新日期：2009-04-01 00:00:00

abstract：:Over the past almost 50 years several calcium concentrations in the dialysate (CaD) have been used to balance calcium in hemodialysis (HD) patients but a consensus as to which is most appropriate has not been established. Moreover, since the late 1980s, further confusion has been caused following the use of calcium sa...

journal_title：Clinical nephrology

authors： Seyffart G,Schulz T,Stiller S

更新日期：2009-03-01 00:00:00

abstract：AIMS:Spontaneous hemorrhage in the kidney, also known as Wunderlich Syndrome, is a rare clinical problem. The most common cause of spontaneous renal hemorrhage is tumor. Other causes are rupture of a renal cyst, vasculitis, hydronephrosis, preeclampsia, and kidney infections. CASE HISTORY:A 67-year-old man was admitte...

journal_title：Clinical nephrology

authors： Capitanini A,Tavolaro A,Rosellini M,Rossi A

更新日期：2009-03-01 00:00:00

abstract：:We describe an elderly man with membranous nephropathy and lymphoplasmacytic infiltration into the renal interstitium who presented with a high serum IgG4 concentration and no organ involvement in the pancreatobiliary system. Although the patient had hypocomplementemia and was positive for antinuclear antibodies, he w...

journal_title：Clinical nephrology

authors： Saeki T,Imai N,Ito T,Yamazaki H,Nishi S

更新日期：2009-02-01 00:00:00

abstract：:Patients with renal failure sometimes develop nephrogenic systemic fibrosis (NSF) following administration of gadolinium, and a few cases have been reported in Japan. There is no definitive cure; the disease is progressive and can be fulminant. We report a case of a 54-year-old woman with multiple pathologies, includi...

journal_title：Clinical nephrology

authors： Nakai K,Takeda K,Kimura H,Miura S,Maeda A

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Increased cardiac troponin T (cTnT) and C-reactive protein (CRP) levels predict mortality in patients with end-stage renal disease (ESRD) on maintenance hemodialysis. Obstructive sleep apnea (OSA) is associated with severe cardiac stress and systemic inflammation. We hypothesized that in patients with ESRD e...

journal_title：Clinical nephrology

authors： Koehnlein T,Schmidt A,Moesenthin M,Dierkes J,Neumann KH,Welte T

更新日期：2009-01-01 00:00:00